The Journal of Organic Chemistry

Peptide decomposition in the neutral pH region via the formation of diketopiperazines

SM Steinberg, JL Bada

Index: Steinberg, Spencer M.; Bada, Jeffrey L. Journal of Organic Chemistry, 1983 , vol. 48, # 13 p. 2295 - 2298

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Citation Number: 78

Abstract

(11) Stork, G.; Maldonado, L. J. Am. Chem. SOC. 1971,93,5286-5287. (12) Lit. [a]#), +39O (c 5, CHC13), ref 15b. (13) Determined by GC analysis (base-line separation) of (R)-(+)- MTPA esters. Dale, J. A.; Dull, D. L.; Mcmher, H. SJ Org. Chem. 1969, (14) Lit. mp 54-55 OC, [amD -176' (c 0.83, C&). Noe, CR Chem. Ber. 1982,115, 1591-1606. (15) See inter alia: (a) Anhoury, ML; Crooy, P.; De Neys, R.; Eliaers, JJ Chem. Soc., Perkin Tram. 1 1974,1015- ...