Radical-based syntheses of 5-benzoyl-1, 2-dihydro-3H-pyrrolo [1, 2-a] pyrrole-1-carboxylic acid (ketorolac)

DR Artis, IS Cho, JM Muchowski

Index: Artis; Cho; Muchowski Canadian Journal of Chemistry, 1992 , vol. 70, # 6 p. 1838 - 1842

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Citation Number: 43

Abstract

DEAN R. ARTIS, IN-SEOP CHO, and JOSEPH M. MUCHOWSKI. Can. J. Chem. 70, 1838 (1992). Short, efficient, and convergent syntheses of ketorolac (1) based on the inter- or intramolecular oxidative addition of malonyl and substituted malonyl radicals to 2-benzoylpyrrole and derivatives