Chemistry Letters

TiCl4-Zn Induced Reductive Acylation of Ketones with Acylsilanes.

H Sakurai, Y Imamoto, T Hirao

Index: Sakurai, Hidehiro; Imamoto, Yuka; Hirao, Toshikazu Chemistry Letters, 2002 , # 1 p. 44 - 45

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Citation Number: 3

Abstract

Since the discovery by Mukaiyama,1 Tyrlik,2 and McMurry,3 one- and/or two-electron reduction of carbonyl compounds induced by a low-valent titanium have provided a variety of important organic transformations such as symmetrical 1,2-diol formation (pinacol coupling) and alkene formation (McMurry coupling).4 Recent reports from our laboratory have demon- strated highly diastereoselective pinacol coupling reactions using a catalytic amount of titanium or ...