Formal Total Synthesis of Fostriecin by 1, 4??Asymmetric Induction with an Alkyne–Cobalt Complex
Y Hayashi, H Yamaguchi, M Toyoshima…
Index: Hayashi, Yujiro; Yamaguchi, Hirofumi; Toyoshima, Maya; Okado, Kotaro; Toyo, Takumi; Shoji, Mitsuru Chemistry - A European Journal, 2010 , vol. 16, # 33 p. 10150 - 10159
Full Text: HTML
Citation Number: 27
Abstract
Abstract The synthesis of a protected dephosphofostriecin, and thereby a formal synthesis of fostriecin, has been accomplished. The synthetic challenges were the construction of four stereogenic centers and the conformationally labile cis-cis-trans-triene moiety. Previous total syntheses have employed at least two asymmetric reactions that required the use of an external chiral auxiliary. Although remote stereoinduction in a 1, 4-relationship is ...
Related Articles:
Modular Total Synthesis of Rhizopodin: A Highly Potent G??Actin Dimerizing Macrolide
[Kretschmer, Manuel; Dieckmann, Michael; Li, Pengfei; Rudolph, Sven; Herkommer, Daniel; Troendlin, Johannes; Menche, Dirk Chemistry - A European Journal, 2013 , vol. 19, # 47 p. 15993 - 16018]
Stereoselective Synthesis of (−)??Pinidinone
[Shankaraiah, Gundeti; Vijaya Kumar, Tiruvayamudi; Venkateswara Reddy, Guvvala; Madhusudana Rao, Janaswamy; Suresh Babu, Katragadda Helvetica Chimica Acta, 2013 , vol. 96, # 5 p. 990 - 996]
A short enantioselective synthesis of a component of cryptophycin A and arenastatin A
[Furuyama, Masaaki; Shimizu, Isao Tetrahedron Asymmetry, 1998 , vol. 9, # 8 p. 1351 - 1357]
A very practical and selective method for PMB protection of alcohols
[Chavan, Subhash P.; Harale, Kishor R. Tetrahedron Letters, 2012 , vol. 53, # 35 p. 4683 - 4686]
Anodic Oxidation: An Attractive Alternative to CAN??Mediated Cleavage of para??Methoxyphenyl Ethers
[Vaxelaire, Carine; Souquet, Florence; Lannou, Marie-Isabelle; Ardisson, Janick; Royer, Jacques European Journal of Organic Chemistry, 2009 , # 19 p. 3138 - 3140]