Analogs of Pteroylglutamic Acid. IX. Derivatives with Substituents on the Benzene Ring1

DB Cosulich, DR Seeger, MJ Fahrenbach…

Index: Cosulich et al. Journal of the American Chemical Society, 1953 , vol. 75, p. 4675,4680

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Citation Number: 14

Abstract

A series of pteroylglutamic acid derivatives has been synthesized with halogen and methyl substituents in the benzene ring moiety. The nitration of pteroylglutamic acid and 4-ami~ opteroylglutamic acid has been investigated. A number of new nitrobenzoic and nitrobenzoylglutamic acid derivatives have been synthesized as intermediates and reference compounds.