O, O-Diethyl dithiophosphoric acid mediated direct synthesis of thioamides from aldehydes and ketones
AK Yadav, VP Srivastava, LDS Yadav
Index: Yadav, Arvind K.; Srivastava, Vishnu P.; Yadav, Lal Dhar S. Tetrahedron Letters, 2012 , vol. 53, # 52 p. 7113 - 7116
Full Text: HTML
Citation Number: 11
Abstract
A general and convenient method for a one-pot conversion of aldehydes and ketones into thioamides has been developed. The protocol involves oximation of aldehydes and ketones followed by deoxygenative thioamidation of oximes with O, O-diethyl dithiophosphoric acid which acts as an acid as well a source of sulfur. The method is operationally simple, high yielding, and also applicable to the conversion of amides and nitriles into the ...
Related Articles:
P 4 S 10/dimethicone tandem: efficient reagent for thionation of various aromatic amides and esters
[Cho, Dongho; Ahn, Jiyoung; De Castro, Kathlia A.; Ahn, Hyunseok; Rhee, Hakjune Tetrahedron, 2010 , vol. 66, # 30 p. 5583 - 5588]
Thermodynamic scales for sulfur atom transfer and oxo-for-sulfido exchange reactions
[Shabana, R.; Meyer, H.J.; Lawesson, S.-O. Phosphorus and Sulfur and the Related Elements, 1985 , vol. 25, p. 297 - 306]
[Brembilla, Alain; Roizard, Denis; Schoenleber, Jacqueline; Lochon, Pierre Canadian Journal of Chemistry, 1984 , vol. 62, p. 2330 - 2336]
[Brembilla, Alain; Roizard, Denis; Schoenleber, Jacqueline; Lochon, Pierre Canadian Journal of Chemistry, 1984 , vol. 62, p. 2330 - 2336]
[Conole, Daniel; Beck, Thorsten M.; Jay-Smith, Morgan; Tingle, Malcolm D.; Eason, Charles T.; Brimble, Margaret A.; Rennison, David Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 7 p. 2220 - 2235]