Tetrahedron

Syntheses of 3b, 4, 6, 7-Tetrahydro-5h, 9h-pyrazino [2, 1-c] phyrolo [1, 2-a][1, 4] benzodiazepine, a valuable precursor of potential central nervous system agents

S Massa, A Mai, M Artico, F Corelli, M Botta

Index: Massa; Mai; Artico; Corelli; Botta Tetrahedron, 1989 , vol. 45, # 9 p. 2763 - 2772

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Citation Number: 17

Abstract

Two alternative routes to 3b, 4, 6, 7-tetrahydro-4H, 9H-pyrazino [2, 1-c] pyrrolo [1, 2-a][1, 4] benzodiazepine, a useful intermediate for the synthesis of potential antidepressant agents, are described. Though following conceptually different synthetic approaches, both procedures lead to the title compound in a simple and profitable way.