Efficient Copper-Catalyzed Double S-Arylation of Aryl Halides with Sodium Sulfide in Peg-400

J Chen, Y Zhang, L Liu, T Yuan, F Yi

Index: Chen, Junmin; Zhang, Yimin; Liu, Li; Yuan, Tangjun; Yi, Fei Phosphorus, Sulfur and Silicon and the Related Elements, 2012 , vol. 187, # 11 p. 1284 - 1290

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Citation Number: 6

Abstract

An efficient copper-catalyzed double S-arylation of sodium sulfide with aryl halides in PEG-400 has been developed. With CuI as a catalyst and PEG-400 as a solvent, a range of electron-withdrawing or electron-donating aryl iodides and aryl bromides were found to be applicable to the environmentally benign system. The present procedure is mild and tolerant of a variety of functional groups and the steric hindrance of ortho-substituents on aryl halides did not affect the outcome of ...