Preparation of aryl and heteroaryl indium (III) reagents by the direct insertion of indium in the presence of LiCl

YH Chen, P Knochel

Index: Chen, Yi-Hung; Knochel, Paul Angewandte Chemie - International Edition, 2008 , vol. 47, # 40 p. 7648 - 7651

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Citation Number: 77

Abstract

Functionalized organometallic compounds are key intermediates in organic synthesis.[1] In particular, organozinc reagents are compatible with a wide range of functional groups and have broad application in synthesis.[2] However, sensitive functional groups, such as aldehyde or ketone functionalities with α acidic hydrogen atoms, are only tolerated in special cases.[3] Furthermore, the reactivity of unsaturated zinc reagents toward acidic hydrogen ...