Scope and Post??Transformations for the Borane??Isocyanide Multicomponent Reactions: Concise Access to Structurally Diverse Heterocyclic Compounds

…, E Vicente??García, M Revés, N Isambert…

Index: Kielland, Nicola; Vicente-Garcia, Esther; Reves, Marc; Isambert, Nicolas; Arevalo, Maria Jose; Lavilla, Rodolfo Advanced Synthesis and Catalysis, 2013 , vol. 355, # 16 p. 3273 - 3284

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Citation Number: 5

Abstract

Abstract: A recently described family of multicomponent reactions (MCRs) involving isocyanides, aldehydes, dipolarophiles and alkylboranes that yield highly substituted aziridines, oxazolidines and pyrrolidines has been studied in detail. In this work the scope of these processes is significantly increased by preparing the borane input through hydroboration of alkenes or organometallic processes, in tandem with the MCR. The ...