Organic letters

Highly Regio-and Diastereoselective Formation of Tetrasubstituted (Z)-1, 2-Dihaloalkenes from the Halogenation of Trimethylsilyl Alkynes with ICl

KC Sproul, WA Chalifoux

Index: Larson, Steven; Luidhardt, Teresa; Kabalka, George W.; Pagni, Richard M. Tetrahedron Letters, 1988 , vol. 29, # 1 p. 35 - 36

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Abstract

... Volume: Page: ... Organic Letters. ... work with the addition of BrCl to electron-deficient substrates.(19) The ICl addition to alkyl derivatives such as 1-(TMS)-hexyne (6i) to produce 7i also worked, where BrCl fails,(19) resulting in only a modest 3:1 selectivity in ...

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