The Preparation of Synthetic Estrogens. V. 1 New Routes to 3, 3-Bis-(p-hydroxyphenyl)-4-hexanone and the Allied Substances

K Sisido, H Nozaki, O Kurihara

Index: Sisido et al. Journal of the American Chemical Society, 1950 , vol. 72, p. 2270

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Citation Number: 1

Abstract

3, 3-Bis-(p-hy droxyphen yl)-4-hexanone and its derivatives, viz., ethers and esters, have been used as key intermediates in the synthesis of diethylstilbe~ trol.~~~*~ In the first paper of this series4 we described a preparation of the ketone by a pinacolone rearrangement of 3, 4-di-p-anisyl-3, 4-hex-anediol as well as the succeeding conversion of the product to diethylstilbestrol. In the course of subsequent investigations we have developed new ...