335. The reduction of juglone
RH Thomson
Index: Thomson Journal of the Chemical Society, 1951 , p. 1237 Journal of the Chemical Society, 1952 , p. 1822
Full Text: HTML
Citation Number: 3
Abstract
The yellow compound previously obtained by hydrogenolysis of 3-carboxymethylthiojuglone (I; R= H) with Raney nickel is shown to be 5: 8-dihydroxy-1-tetralone (VI; R= H) arising by further reduction of a-hydrojugione (11). Similar treatment of P-hydrojuglone gives the keto- alcohol (IV). IN the preparation of plumbagin (2-methyljuglone) by hydrogenolysis of (I; R= Me) with Raney nickel, a small amount of a yellow by-product (A), mp 164", was isolated (J ...
Related Articles:
Preparation of Naphthoquinone Derivatives from Plumbagin and Their Ichthyotoxicity.
[Ogihara, Kazuhito; Yamashiro, Rieko; Higa, Matsutake; Yogi, Seiichi Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 3 p. 437 - 445]