Organobis (cuprates): a new class of reagents and method for spiroannelation
PA Wender, AW White
Index: Wender, Paul A.; White, Alan W. Journal of the American Chemical Society, 1988 , vol. 110, # 7 p. 2218 - 2223
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Citation Number: 69
Abstract
Abstract: A one-step spiroannelation method applicable to the synthesis of the commonly encountered spirocyclic systems is described. The method involves the reaction of 3- halocycloalk-2-enones with a new type of cuprate reagent prepared from organodilithium reagents and copper thiophenoxide and is shown to provide efficient am to spiro [4.4] nonanes, spiro [4S] dmnes, and spiro [5S] undecanes. The effects of temperature, ...
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