CAN-catalyzed three-component reaction between anilines and alkyl vinyl ethers: stereoselective synthesis of 2-methyl-1, 2, 3, 4-tetrahydroquinolines and studies on …
V Sridharan, C Avendano, JC Menéndez
Index: Sridharan, Vellaisamy; Avendano, Carmen; Menendez, J. Carlos Tetrahedron, 2007 , vol. 63, # 3 p. 673 - 681
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Citation Number: 65
Abstract
The CAN-catalyzed reaction between anilines and vinyl ethers at room temperature provides a convenient and efficient access to 4-alkoxy-2-methyl-1, 2, 3, 4- tetrahydroquinolines. This reaction is stereoselective, favouring a cis arrangement for the alkoxy and methyl groups, and involves a three-component process that leaves a molecule of alcohol as the only side product. 2-Methylquinoline derivatives were efficiently prepared ...
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