Polymer

Release kinetics and cellular profiles for bFGF-loaded electrospun fibers: Effect of the conjugation density and molecular weight of heparin

J Zou, Y Yang, Y Liu, F Chen, X Li

Index: Zou, Jie; Yang, Ye; Liu, Yaowen; Chen, Fang; Li, Xiaohong Polymer, 2011 , vol. 52, # 15 p. 3357 - 3367

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Citation Number: 14

Abstract

The integration mode and release modulation of growth factors inside the scaffolds represent major challenges for inductive tissue regeneration. The integration of the bioaffinity of heparin with growth factors and the biomimicry of electrospun fibrous network to extracellular matrices is expected to efficiently bind and gradually release growth factors. Functional ketone groups were incorporated into poly (dl-lactide) backbone through ...