Tetrahedron

Isoaurones: synthesis and stereochemical assignments of geometrical isomers

S Venkateswarlu, GK Panchagnula, MB Guraiah…

Index: Venkateswarlu, Somepalli; Panchagnula, Gopala K.; Guraiah, Mothukuri Bala; Subbaraju, Gottumukkala V. Tetrahedron, 2006 , vol. 62, # 42 p. 9855 - 9860

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Citation Number: 18

Abstract

A series of isoaurones have been synthesized for the first time from substituted acetophenones via benzo-2 (3H)-furanone in three steps. Geometrical isomers of the isoaurones were separated. The differences in the proton and carbon NMR spectra of the E- and Z-isoaurones afford a useful method for distinguishing between the two isomers. Marginalin, a metabolite of Dytiscus marginalis has been synthesized and the spectral ...