4-Amino-6-(trichloroethenyl)-1, 3-benzenedisulfonamide, a new, potent fasciolicide

H Mrozik, RJ Bochis, P Eskola, A Matzuk…

Index: Mrozik; Bochis; Eskola; Matzuk; Waksmunski; Olen; Schwartzkopf Jr.; Grodski; Linn; Lusi; Wu; Shunk; Peterson; Milkowski; Hoff; Kulsa; Ostlind; Campbell; Riek; Harmon Journal of Medicinal Chemistry, 1977 , vol. 20, # 9 p. 1225 - 1227

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Citation Number: 18

Abstract

Chemistry. The 3-(trichloroethenyl) aniline (3) required as starting material was obtained by reduction of 3-(pentachloroethyl) aniline6 (2) with zinc in ethanol or by reduction of 3- (pentach10roethyl) nitrobenzene~(1) with iron in aqueous ethanol containing a catalytic amount of hydrochloric acid. Compound 3 was described6 as a reduction product of 3- (trichloroethenyl) nitrobemne, which had been obtained by nitration of ...