PtCl 2/XPhos: A highly efficient and readily available catalyst for the hydrosilylation of propargylic alcohols

MG McLaughlin, MJ Cook

Index: McLaughlin, Mark G.; Cook, Matthew J. Chemical Communications, 2011 , vol. 47, # 39 p. 11104 - 11106

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Citation Number: 24

Abstract

A solution to this problem was found through the use of bulky trialkylphosphine ligands 6 and more recently the use of platinum N-heterocyclic carbene complexes. 7 These sterically encumbered catalysts can impart high levels of selectivity on the reactions. Of note, was the development of the (dvs)Pt–Pt–Bu 3 catalyst which exhibits high activity with a high level of selectivity. 6a The drawbacks to these methods are the cost of the Pt(0) precatalysts and the pyrophoric ...