N??Heterocyclic Carbene Catalyzed Umpolung of Michael Acceptors for Intermolecular Reactions
…, M Padmanaban, NE Wurz, F Glorius
Index: Biju, Akkattu T.; Padmanaban, Mohan; Wurz, Nathalie E.; Glorius, Frank Angewandte Chemie - International Edition, 2011 , vol. 50, # 36 p. 8412 - 8415
Full Text: HTML
Citation Number: 89
Abstract
The benzoin reaction, the coupling of two aromatic aldehydes [Eq.(1)], is one of the most important transformations catalyzed by N-heterocyclic carbenes (NHCs).[1] It proceeds through a unique umpolung strategy, which is widely used to provide unconventional access to various target molecules.[2] Intriguingly, however, in most cases this strategy is limited to aldehydes,[3] and the umpolung of other electrophiles in this realm of NHC ...
Related Articles:
[Hoffmann, H. Martin R.; Rabe, Juergen Journal of Organic Chemistry, 1985 , vol. 50, # 20 p. 3849 - 3859]
2-Pyrimidylphosphines: A new class of ligands for transition metal catalysis
[Reetz, Manfred T.; Demuth, Ralf; Goddard, Richard Tetrahedron Letters, 1998 , vol. 39, # 39 p. 7089 - 7092]
Doubly Deprotonated Methyl 3??Mitropropanoate, an Acrylic Ester d2??reagent
[Seebach, Dieter; Henning, Rainer; Mukhopadhyay, Triptikumar Chemische Berichte, 1982 , vol. 115, # 5 p. 1705 - 1720]
[Rabe, Juergen; Hoffmann, H. M. R. Angewandte Chemie, 1983 , vol. 95, # 10 p. 796 - 797]
[Baudin, Jean-Bernard; Julia, Sylvestre A. Tetrahedron Letters, 1988 , vol. 29, # 26 p. 3255 - 3258]