Tetrahedron

Synthesis of deoxyribotetranucleotides by the cyclic enediol phosphorylation method

F Ramirez, TE Gavin, SB Mandal, SV Kelkar…

Index: Ramirez, Fausto; Gavin, Trerence E.; Mandal, Sukhendu B.; Kelkar, Shripad V.; Marecek, James F. Tetrahedron, 1983 , vol. 39, # 13 p. 2157 - 2161

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Citation Number: 7

Abstract

Full experimental details are given for the application of the di (1, 2-dimethylethenylene) pyrophosphate method of phosphodiester synthesis to the conversion of deoxyribonucleosides into deoxyribodinucleotides in the dG, dA, dC and dT families. N-(1, 2- dimethylethenylenedioxyphosphoryl) imidazole is superior to the corresponding pyrophosphate as a reagent for the conversion of deoxyribodinucleotides into ...