5-(Tetradecyloxy)-2-furancarboxylic acid and related hypolipidemic fatty acid-like alkyloxyarylcarboxylic acids

RA Parker, T Kariya, JM Grisar…

Index: Parker,R.A. et al. Journal of Medicinal Chemistry, 1977 , vol. 20, p. 781 - 791

Full Text: HTML

Citation Number: 66

Abstract

mmol) of THF containing 5% CH3NH2 was stirred for 73.5 h at room temperature. After removal of solvent in vacuo the residue was extracted with CH2C12. The CHzClz extracts were washed with HzO, dried over Na2S04, filtered, and evaporated to give a residue which was chromatographed on silica gel. The residue of fractions eluted with CH2C12 was collected and washed with isopropyl ether to give 574 mg (83%, mp 248-250" C) of 9j. ...