Tumor immunity requires border patrol to fight the enemy within

Derk Amsen, Pleun Hombrink, Rene A W van Lier

Index: 10.1038/ni.3792

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Abstract

The infiltration of solid tumors by CD8+ T cells is a favorable prognostic marker. Large-scale transcriptome analysis of tumor-infiltrating T cells from mucosal tumors shows that CD8+ T cells with a CD103+ tissue-resident memory T cell phenotype might be the most desirable.