Nature Immunology 2017-07-19

Counting the cost of lineage decisions

Alberto Yáñez, Helen S Goodridge, H Leighton Grimes

Index: 10.1038/ni.3794

Full Text: HTML

Abstract

Lineage bias among early hematopoietic progenitor cells is specified by transcription-factor programming, and lineage switching reduces the quantity of cells produced.

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