Tetrahedron

Preparation of the MacMillan imidazolidinones

L Samulis, NCO Tomkinson

Index: Samulis, Leopold; Tomkinson, Nicholas C.O. Tetrahedron, 2011 , vol. 67, # 23 p. 4263 - 4267

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Citation Number: 16

Abstract

Abstract A general method for the preparation of the MacMillan imidazolidinones is described. Treatment of an α-amino amide with a carbonyl compound in refluxing chloroform in the presence of Yb (OTf) 3 (1 mol%) provides convenient access to the corresponding imidazolidinones.

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