Generation of Human Hair Cells In Vitro: Is It All about How the Wnt Blows?

Matthew W. Kelley

Index: 10.1016/j.stem.2017.06.007

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Abstract

Screening for small molecules or drugs that can protect or restore mechanosensory hair cells has been hampered by limited cell numbers. InNature Biotechnology, Koehler et al. (2017) have developed a human organoid-based approach using basic developmental principles to generate large numbers of bonafide hair cellsin vitro.