A checkpoint to pain
Michael Hirth, Jagadeesh Gandla, Rohini Kuner
Index: 10.1038/nn.4586
Full Text: HTML
Abstract
The checkpoint pathway consisting of programmed death ligand 1 (PD-L1) and its receptor, PD-1, modulates immune function in cancer and infection, but unexpectedly, it also silences pain signals in nerves.
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