Neurotropic and psychotropic substances. XXVI. Derivatives of indole, benz [c, d] indole, benzimidazole and 3-benzazepine

K Pelz, M Rajšner, JO Jílek…

Index: Pelz,K. et al. Collection of Czechoslovak Chemical Communications, 1968 , vol. 33, # 7 p. 2111 - 2120

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Citation Number: 4

Abstract

Alkylation of indole, 1, 3, 4, 5-tetrahydrobenz [c, d] indole (II!), naphtostyril (V), 2- (phenoxymethyl) benzimidazole (IX), 2, 3, 4, 5-tetrahydro-1H-3-benzazepin-2-one (XIII) and 2, 3, 4, 5-tetrahydro-1H-3-benzazepine (XVI) with 3-dimethylaminopropyl chloride, 2- dimethylaminoethyl chloride and propargyl bromide yielded bases I, IV, VI, X, XI, XIV, XV, XVII and XVIII. Further transformations of the aminolactam VI yielded bases VII and VIII. ...