Studies on tertiary amine oxides. LXVII. Reactions of aromatic N??oxides with 3??arylrhodanines in the presence of acetic anhydride

MM Yousif, S Saeki, M Hamana

Index: Yousif, Mohammed M.; Saeki, S.; Hamana, M. Journal of Heterocyclic Chemistry, 1980 , vol. 17, p. 305 - 309

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Citation Number: 4

Abstract

Abstract Quinoline 1-oxides 1 readily react with 3-arylrhodanines 2 in the presence of acetic anhydride to afford 3-aryl-5-(2-quinolyl) rhodanines 3 in high yields. These products resist hydrolysis under both alkaline and acidic conditions, but is oxidized to quinaldinic acid 1- oxide 4 with 30% hydrogen peroxide in hot acetic acid. Besides isoquinoline 2-oxide 5, pyridine 1-oxide 7a also reacts in the same way to give 3-aryl-5-(2-pyridyl) rhodanines 8, ...