Repeal and Replace: Adipocyte Regeneration in Wound Repair

Valerie Horsley, Fiona Watt

Index: 10.1016/j.stem.2017.03.015

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Abstract

Adipocyte precursor cells generate lipid-filled mature adipocytes in multiple tissues during a high-fat diet and in skin during hair follicle growth. In Science, Plikus et al. report that myofibroblasts can generate lipid-filled adipocytes in large skin wounds that regenerate hair follicles, suggesting a new source of adipogenic progenitor cells.