Investigations concerning the organolanthanide and group 3 metallocene-catalyzed cyclization–functionalization of nitrogen-containing dienes

GA Molander, JAC Romero

Index: Molander, Gary A.; Romero, Jan Antoinette C. Tetrahedron, 2005 , vol. 61, # 10 p. 2631 - 2643

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Citation Number: 25

Abstract

Organolanthanide catalyzed cyclization–silylation of nitrogen-containing polyunsaturated systems allows access to core structures commonly found in naturally occurring alkaloids. Nitrogen-containing dienes with various substitution patterns were investigated. The method was most successful for substrates with terminal alkenes. Cyclization upon pendant 1, 1- disubstituted olefins was not realized under various conditions. Interestingly, sterically ...