Antimalarial phenanthrene amino alcohols. 3. Halogen-containing 9-phenanthrenemethanols

EA Nodiff, AJ Saggiomo, K Tanabe…

Index: Nodiff,E.A. et al. Journal of Medicinal Chemistry, 1975 , vol. 18, p. 1011 - 1019

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Citation Number: 9

Abstract

A series of new 9-phenanthrene amino alcohols has been prepared in which each compound bears from one to five halogen or halogen-containing moieties. A number of these compounds are extremely active against Plasmodium berghei in the mouse. Some structural requirements for optimal efficacy are considered.