Tetrahedron letters

Highly selective mono-substitution in Pd-catalyzed cross-coupling reactions of 3, 6-dichloropyridazine with organozinc compounds

DS Chekmarev, AE Stepanov, AN Kasatkin

Index: Chekmarev, Dmitriy S.; Stepanov, Alexander E.; Kasatkin, Alexander N. Tetrahedron Letters, 2005 , vol. 46, # 8 p. 1303 - 1305

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Citation Number: 15

Abstract

Pd-catalyzed cross-coupling reactions of 3, 6-dichloropyridazine () with benzyl, aryl, and alkyl organozinc compounds led to selective mono-substitution of one of the chlorine atoms. The subsequent cross-coupling of the resulting monochlorides with RZnCl afforded ...