gem-Dialkyl effect in medicinal agents

MS Newman, WJJ Broger, JB LaPidus…

Index: Newman; Broger; LaPidus; Tye Journal of medicinal chemistry, 1972 , vol. 15, # 10 p. 1003 - 1006

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Citation Number: 5

Abstract

The preparation of four series of compounds (cholinergic agonists, postganglionic cholinergic antagonists, antihistamines, and local anesthetics), all containing gem-dialkyl groups in the alkanolamine portion, is described, and their biological activities are reported.