A simple and efficient one-pot synthesis of 2-substituted benzimidazoles
K Bahrami, MM Khodaei, I Kavianinia
Index: Bahrami, Kiumars; Khodaei, Mohammad Mehdi; Kavianinia, Iman Synthesis, 2007 , # 4 p. 547 - 550
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Citation Number: 121
Abstract
Abstract A simple and efficient procedure for the synthesis of substituted benzimidazoles through a one-pot condensation of o-phenylenediamines with aryl aldehydes in the presence of H 2 O 2/HCl system in acetonitrile at room temperature is described. Short reaction time, large-scale synthesis, easy and quick isolation of the products, and excellent yields are the main advantages of this procedure.
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