Cyclization of Acylaminoalkanols to 2-Oxazolines1
RN Boyd, RC Rittner
Index: Boyd,R.N.; Rittner,R.C. Journal of the American Chemical Society, 1960 , vol. 82, p. 2032 - 2034
Full Text: HTML
Citation Number: 14
Abstract
Through the use of o-toluenesulfonyl chloride and pyridine it has been found possible to form 2-oxazolines from acylaminonlkanols in which the amido group is attached to primary, secondary or tertiary carbon, and the alcohol is primary or secondary. The yield of oxazoline ranged from 21-85y0 depending upon the structure of the ncylaminoalkanol. Sulfonic acid esters are suggested as intermediates.
Related Articles:
Facile syntheses of oxazolines and thiazolines with N-acylbenzotriazoles under microwave irradiation
[Katritzky, Alan R.; Cai, Chunming; Suzuki, Kazuyuki; Singh, Sandeep K. Journal of Organic Chemistry, 2004 , vol. 69, # 3 p. 811 - 814]
Facile syntheses of oxazolines and thiazolines with N-acylbenzotriazoles under microwave irradiation
[Katritzky, Alan R.; Cai, Chunming; Suzuki, Kazuyuki; Singh, Sandeep K. Journal of Organic Chemistry, 2004 , vol. 69, # 3 p. 811 - 814]