One-pot combination of enzyme and Pd nanoparticle catalysis for the synthesis of enantiomerically pure 1, 2-amino alcohols

…, B Grischek, W Kroutil, N d'Alessandro, F Hollmann

Index: Schrittwieser, Joerg H.; Coccia, Francesca; Kara, Selin; Grischek, Barbara; Kroutil, Wolfgang; D'Alessandro, Nicola; Hollmann, Frank Green Chemistry, 2013 , vol. 15, # 12 p. 3318 - 3331

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Citation Number: 17

Abstract

One-pot combinations of sequential catalytic reactions can offer practical and ecological advantages over classical multi-step synthesis schemes. In this context, the integration of enzymatic and chemo-catalytic transformations holds particular potential for efficient and selective reaction sequences that would not be possible using either method alone. Here, we report the one-pot combination of alcohol dehydrogenase-catalysed asymmetric ...