Beilstein journal of organic chemistry

Molecular recognition of isomeric protonated amino acid esters monitored by ESI-mass spectrometry

A Liesenfeld, A Lützen

Index: Liesenfeld, Andrea; Lutzen, Arne Beilstein Journal of Organic Chemistry, 2014 , vol. 10, p. 825 - 831

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Citation Number: 2

Abstract

Abstract Two new 9, 9'-spirobifluorene-derived crown ethers were prepared and used to recognise constitutionally isomeric amino acid derivatives. The performance of the receptors was evaluated by ESI-mass spectrometry using the isomer labelled guest method (ILGM). This method revealed the preferred binding of L-norleucine and L-leucine compared to L- isoleucine for both receptors. Furthermore, non-covalent isotope effects demonstrate the ...

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