Synthesis and Application of 2, 6??Bis (trifluoromethyl)??4??pyridyl Phosphanes: The Most Electron??Poor Aryl Phosphanes with Moderate Bulkiness

T Korenaga, A Ko, K Uotani, Y Tanaka…

Index: Korenaga, Toshinobu; Ko, Aram; Uotani, Kotaro; Tanaka, Yuki; Sakai, Takashi Angewandte Chemie - International Edition, 2011 , vol. 50, # 45 p. 10703 - 10707

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Citation Number: 36

Abstract

In transition-metal catalysis, PPh3 and more electron-rich tertiary phosphanes are popular ligands for controlling catalytic activity and selectivity. In contrast, efficient catalysts using highly electron-poor phosphanes,[1] such as P (C6F5) 3, have rarely been reported. However, in recent years this phosphane has been used as an effective ligand, particularly in gold [2] or iridium [3] catalysts. Furthermore, a prominent ligand-acceleration effect (LAE ...