Tetrahedron

Rapid access to 4-substituted-pyrones and 2 (5H)-furanones via a palladium-catalyzed C–OH bond activation

Y Hu, Q Ding, S Ye, Y Peng, J Wu

Index: Hu, Yi; Ding, Qiuping; Ye, Shengqing; Peng, Yiyuan; Wu, Jie Tetrahedron, 2011 , vol. 67, # 38 p. 7258 - 7262

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Citation Number: 8

Abstract

An efficient palladium-catalyzed cross-coupling reaction of 4-hydroxy-pyrone or 4-hydroxy-2 (5H)-furanone with arylboronic acid is described, which affords the 4-substituted-pyrones and 2 (5H)-furanones in good yields. This transformation proceeds through a C–OH bond activation under mild conditions.

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