Research on Chemical Intermediates

Selective reduction of nitroarenes to N-arylhydroxylamines by use of Zn in a CO2–H2O system, promoted by ultrasound

S Liu, Y Wang, X Yang, J Jiang

Index: Liu, Shijuan; Wang, Yanhua; Yang, Xun; Jiang, Jingyang Research on Chemical Intermediates, 2012 , vol. 38, # 9 p. 2471 - 2478

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Citation Number: 8

Abstract

Abstract The promoting effect of ultrasound on the selective reduction of nitroarenes to N- arylhydroxylamines by use of Zn in an environmentally benign CO 2–H 2 O system has been demonstrated. The yield of N-phenylhydroxylamine reaches 95% when the reaction is carried out with a Zn-to-nitrobenzene molar ratio of 2.2 under ultrasound (40 kHz) at 25° C and normal pressure of CO 2 for 60 min. Application of ultrasound to the reaction has the ...