Synthesis of dipeptides from N-hydroxy-3-azaspiro [5, 5] undecane-2, 4-dione activated α-amino acids
S Nowshuddin, AR Reddy
Index: Nowshuddin, Shaik; Ram Reddy Tetrahedron Asymmetry, 2011 , vol. 22, # 1 p. 22 - 25
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Citation Number: 4
Abstract
A simple two step procedure for the synthesis of a dipeptide from N-hydroxy-3-azaspiro [5, 5] undecane-2, 4-dione (HO-ASUD) activated α-amino acids is described. In presence of DCC, N-hydroxy-3-azaspiro [5, 5] undecane-2, 4-dione readily esterifies the carboxylic acid group
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