Synthesis

Palladium-Catalyzed Direct Arylation-Based Domino Synthesis of Annulated N-Heterocycles Using Alkenyl or (Hetero) Aryl 1, 2-Dihalides

L Ackermann, A Althammer, P Mayer

Index: Ackermann, Lutz; Althammer, Andreas; Mayer, Peter Synthesis, 2009 , # 20 p. 3493 - 3503

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Citation Number: 33

Abstract

Abstract A palladium-catalyzed reaction sequence consisting of an intermolecular amination and an intramolecular direct arylation enabled highly regioselective syntheses of functionalized indoles or carbazoles and proved to be amenable to the use of inexpensive 1, 2-dichloroarenes as electrophiles.

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