Chemistry Letters

Palladium-catalyzed coupling reactions of N-methoxy-N-methylcarbamoyl chloride for the synthesis of N-methoxy-N-methylamides

M Murakami, Y Hoshino, H Ito, Y Ito

Index: Murakami, Masahiro; Hoshino, Yujiro; Ito, Hajime; Ito, Yoshihiko Chemistry Letters, 1998 , # 2 p. 163 - 164

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Citation Number: 24

Abstract

Abstract A new synthetic method of N-methoxy-N-methylamides is developed. The palladium-catalyzed coupling reaction of N-methoxy-N-methylcarbamoyl chloride furnished N-methoxy-N-methylamide in moderate to good yield, wherein a carbonyl equivalent was appended to sp and sp 2 carbon atoms as a versatile synthetic basis for further manipulation.