2-nitroimidazol-5-ylmethyl as a potential bioreductively activated prodrug system: reductively triggered release of the PARP inhibitor 5-bromoisoquinolinone

I Parveen, DP Naughton, WJD Whish…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 14 p. 2031 - 2036

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Citation Number: 50

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... b School of Postgraduate Medicine, University of Bath, Claverton Down, Bath BA2 7AY, UK; c Department of Biology & Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, UK. ...