Transition-metal binding site of bleomycin. Significance of the β-aminoalaninamide appendage in regulating oxygen activation

T Sugiyama, M Ohno, M Shibasaki…

Index: Sugiyama, Toru; Ohno, Masaji; Shibasaki, Masakatsu; Otsuka, Masami; Sugiura, Yukio; et al. Heterocycles, 1994 , vol. 37, # 1 p. 275 - 282

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Citation Number: 15

Abstract

A synthetic model study on the iron-binding site of bleomycin demonstrated that the dioxygen-activating properties of ligands largely depend on the characteristics of functional groups contained in the β-aminoalaninamide moiety. © 1994. ... Sugiyama, T., Ohno, M., Shibasaki, M., Otsuka, M., Sugiura, Y., Kobayashi, S., & Maeda, K. (1994). Transition-metal binding site of bleomycin. Significance of the β-aminoalaninamide appendage in regulating oxygen ...