Palladium-catalyzed, carbonylative, intramolecular coupling of hydroxyvinyl triflates. Synthesis of substituted. alpha.,. beta.-butenolides
GT Crisp, AG Meyer
Index: Crisp, Geoffrey T.; Meyer, Adam G. Journal of Organic Chemistry, 1992 , vol. 57, # 25 p. 6972 - 6975
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Citation Number: 100
Abstract
The a,@-butenolide substructure is found in a wide variety of natural products including many flavor components and insect pheromones." In addition, compounds incorporating functionalized a, &butenolides, or their derivatives, have been shown to be biologically active and some display antitumor activity. lb Although approaches to the syntheais of a#- butenolides have been diverse they can be classified ae either elaboration of an existing ...
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