Helvetica Chimica Acta

A New Method for the Preparation of (E)??3??Acylprop??2??enoic Acids

D Obrecht, B Weiss

Index: Obrecht, Daniel; Weiss, Bettina Helvetica Chimica Acta, 1989 , vol. 72, p. 117 - 122

Full Text: HTML

Citation Number: 25

Abstract

Abstract A new method for the preparation of (E)-3-acylprop-2-enoic acids (=(E)-3- acylacrylic acids) of type IIvia acid-catalyzed isomerization of the corresponding 3-acylprop- 2-ynal acetals of type I (Scheme 1) has been found. The described reaction gives a rapid and quite general access to these compounds known to exhibit a number of interesting biological activities. Some studies toward the elucidation of the reaction mechanism have ...