A novel mode of reactivity for gold (I): The decarboxylative activation of (hetero) aromatic carboxylic acids

J Cornella, M Rosillo??Lopez…

Index: Cornella, Josep; Rosillo-Lopez, Martin; Larrosa, Igor Advanced Synthesis and Catalysis, 2011 , vol. 353, # 8 p. 1359 - 1366

Full Text: HTML

Citation Number: 30

Abstract

Abstract Gold (I) salts are found to mediate the decarboxylation of a variety of aromatic and heteroaromatic carboxylic acids at significatively lower temperatures (as low as 60 C) than the currently used copper (I)(180–190 C) and silver (I)(80–140 C) systems. In contrast to silver (I)-and copper (I)-mediated decarboxylations, the resulting aryl-gold (I) complexes are stable towards protodemetallation and can be readily isolated.

Related Articles:

Efficient one-pot transformation of aminoarenes to haloarenes using halodimethylisulfonium halides generated in situ

[Baik, Woonphil; Luan, Wanqiang; Lee, Hyun Joo; Yoon, Cheol Hun; Koo, Sangho; Kim, Byeong Hyo Canadian Journal of Chemistry, 2005 , vol. 83, # 3 p. 213 - 219]

Electrophilic ipso substitution of trimethylsilyl groups in fluorobenzenes

[Coe, Paul L.; Stuart, Alison M.; Moody, David J. Journal of Fluorine Chemistry, 1998 , vol. 92, # 1 p. 27 - 32]

More Articles...