Synthesis

A new convenient preparation of thiol esters utilizing N-acylbenzotriazoles

AR Katritzky, AA Shestopalov, K Suzuki

Index: Katritzky, Alan R.; Shestopalov, Aleksandr A.; Suzuki, Kazuyuki Synthesis, 2004 , # 11 p. 1806 - 1813

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Citation Number: 24

Abstract

Abstract Diverse thiol esters were synthesized in good to excellent yields (76-99%) by reactions of thiophenol, benzyl mercaptan, ethyl mercaptoacetate, and mercaptoacetic acid with N-acylbenzotriazoles under mild conditions. These results demonstrate the utility of N- acylbenzotriazoles as mild S-acylating agents, especially when the corresponding acid chlorides are not readily available.